Lymph nodes & spleen, nonlymphoma
Lymph nodes-infectious / parasitic disorders
Herpes simplex


Topic Completed: 1 July 2013

Minor changes: 12 October 2020

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PubMed Search: Herpes simplex [title] lymph nodes [title]

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Cite this page: DePond WD. Herpes simplex. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodeshsv.html. Accessed November 26th, 2020.
Definition / general
Case reports
Microscopic (histologic) description
  • Well circumscribed necrosis, follicular and paracortical hyperplasia (Histopathology 1991;19:355)
  • Cells have intranuclear inclusions, particularly at edge of necrotic areas
  • Also marked immunoblasts, T cell hyperplasia
Microscopic (histologic) images

Contributed by Mark R. Wick, M.D.
Missing Image

Herpes simplex lymphadenitis

Positive stains
  • HSV
Electron microscopy description
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