Lymph nodes - not lymphoma
Inflammatory disorders (noninfectious)
Hyaline deposits

Author: William D. DePond, M.D. (see Authors page)

Revised: 29 June 2018, last major update June 2006

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Hyaline deposits lymph node

Cite this page: DePond, W.D. Hyaline deposits. website. Accessed August 17th, 2018.
Definition / general
Microscopic (histologic) description
  • Extracellular eosinophilic material resembling amyloid but Congo Red negative
  • Hyaline sclerosis of small and midsized vessels of lymph nodes and organs (Blood 1995;86:1159)
Microscopic (histologic) images

Images hosted on other servers:

Rheumatoid arthritis and systemic sclerosis:

Hyaline deposits in interfollicular areas

Extensive replacement of node by eosinophilic material (also focal calcification)

Node replaced by
sarcoid-like granulomas
with prominent
hyaline material

Positive stains
  • Immunoglobulins
Negative stains