Lymph nodes & spleen, nonlymphoid
Lymph nodes-infectious / parasitic disorders
Measles


Topic Completed: 1 July 2013

Minor changes: 12 August 2020

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PubMed Search: Measles [title] lymph nodes


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Cite this page: DePond W. Measles. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesmeasles.html. Accessed September 21st, 2020.
Definition / general
  • Live attenuated vaccine may cause regional lymphadenopathy
  • Measles associated lymphopenia may be due to apoptosis of uninfected lymphocytes (Arch Virol 2000;145:905)
  • Fatal measles cases in South African in 1976-1982 were associated with malnutrition; caused depletion of T cell zones (S Afr Med J 1985;68:858)
Case reports
  • 14 month old boy with familial immunodeficiency and necrotizing lymphadenitis with Warthin-Finkeldey type giant cells after measles vaccination (Ultrastruct Pathol 1980;1:243)
Microscopic (histologic) description
  • Polykaryocytes
  • In germinal centers, Warthin-Finkeldey giant cells have large nuclei and B cell markers
  • In interfollicular areas they have small hyperchromatic nuclei and T cell markers (Pathol Int 1994;44:442)
Microscopic (histologic) images

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Measles lymphadenitis

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