Lymph nodes - not lymphoma
Infectious / parasitic disorders
Measles

Author: William D. DePond, M.D. (see Authors page)

Revised: 3 July 2018, last major update July 2013

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Measles [title] lymph nodes

Cite this page: DePond, W. D. Measles. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesmeasles.html. Accessed July 21st, 2018.
Definition / general
  • Live attenuated vaccine may cause regional lymphadenopathy
  • Measles associated lymphopenia may be due to apoptosis of uninfected lymphocytes (Arch Virol 2000;145:905)
  • Fatal measles cases in South African in 1976-1982 were associated with malnutrition; caused depletion of T cell zones (S Afr Med J 1985;68:858)
Case reports
  • 14 month old boy with familial immunodeficiency and necrotizing lymphadenitis with Warthin-Finkeldey type giant cells after measles vaccination (Ultrastruct Pathol 1980;1:243)
Microscopic (histologic) description
  • Polykaryocytes
  • In germinal centers, Warthin-Finkeldey giant cells have large nuclei and B cell markers
  • In interfollicular areas they have small hyperchromatic nuclei and T cell markers (Pathol Int 1994;44:442)
Microscopic (histologic) images

Images hosted on other servers:
Missing Image

Measles lymphadenitis