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Lymph nodes - not lymphoma
Neoplasms (excludes lymphoma)
Myofibroblastoma

Reviewer: William D. DePond, M.D. (see Reviewers page)
Revised: 1 August 2013, last major update June 2006
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

General
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Case reports
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Treatment
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Gross description
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Micro description
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Micro images
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Palisaded tumor with amianthoid fibers

Various images

Fascicles of elongated cells with pale cytoplasm and tapered nuclei

Amianthoid fibers composed of central vessel surrounded by core of collagen with peripheral spokes, Van Gieson+


Mast cells surrounding amianthoid fibers are methylene blue+

Interstitial cells are smooth muscle actin+

Actin stains smooth muscle cells and spokes of amianthoid fibers (arrows)

Early amianthoid fiber formation,
in which a vessel is beginning
to be surrounded by collagen;
overlaying it is an almost fully
formed amianthoid structure; both are
surrounded by proliferating myofibroblasts


Palisaded type - contributed by Dr. Mark R. Wick

Palisaded myofibroblastoma

Cytology description
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Positive stains
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Positive stains
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Electron microscopy description
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Electron microscopy images
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Spindle cell with indented nuclei and parallel collagen fibrils

Differential diagnosis
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Additional references
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End of Lymph nodes - not lymphoma > Neoplasms (excludes lymphoma) > Myofibroblastoma


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