Lymph nodes & spleen, nonlymphoid
Lymph nodes-inclusions, pigment, ectopic cells or tissue
Nevus cells


Topic Completed: 1 July 2013

Minor changes: 12 August 2020

Copyright: 2003-2020, PathologyOutlines.com, Inc.

PubMed Search: Nevus cells [title]

Page views in 2019: 2,218
Page views in 2020 to date: 1,538
Cite this page: DePond W. Nevus cells. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesnevi.html. Accessed September 30th, 2020.
Definition / general
Microscopic (histologic) description
  • Single cells, linear arrangements or aggregates of small, round / oval nevus cells with moderate pale / clear cytoplasm, round nuclei with fine chromatin, no prominent nucleoli or pleomorphism, usually within fibrous capsule and trabeculae, but also within nodal parenchyma (Am J Surg Pathol 2003;27:673) or surrounding a small vessel (Am J Surg Pathol 1996;20:834)
Microscopic (histologic) images

AFIP images
Missing Image

Nevus cells in lymph node



Contributed by Dr. Mark R. Wick
Missing Image Missing Image Missing Image

Nevocytic rest



Images hosted on other servers:
Missing Image

Left-benign nevus
cells, right-infiltrating
lobular carcinoma

Missing Image

Benign nevus cells within
capsule and vessel of
perinodal adipose tissue

Negative stains
Differential diagnosis
  • Blue nevus: also spindled / dendritic cells with heavy pigmentation
  • Metastatic carcinoma or melanoma: usually not confined to capsule, atypia, mitotic figures, different immunostaining
  • Spitz nevus: larger cells with abundant eosinophilic cytoplasm, vesicular nuclei with prominent nucleoli
Back to top
Image 01 Image 02