Lymph nodes & spleen, nonlymphoid
Lymph nodes-inclusions, pigment, ectopic cells or tissue
Yellow bodies

Topic Completed: 1 July 2013

Minor changes: 14 August 2020

Copyright: 2003-2020,, Inc.

PubMed Search: Yellow bodies lymph nodes

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Cite this page: DePond W. Yellow bodies. website. Accessed September 21st, 2020.
Definition / general
  • Also called Hamazaki-Wesenberg bodies
  • More common in deep abdominal than superficial nodes
  • At autopsy, present in 35% of mesenteric nodes and 11% of mediastinal nodes (J Clin Pathol 1979;32:52)
  • No association with age, gender or disease
  • May resemble yeast (Arch Pathol Lab Med 1987;111:555)
Microscopic (histologic) description
  • Small, spindled structures within nodal sinuses or macrophages or lying free
Microscopic (histologic) images

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Missing Image

Mesenteric node shows histiocytes
and heavily stained round, oval and
spindled yellow bodies in a sinus

Positive stains
Electron microscopy description
  • Appear to represent giant lysosomal residual bodies with hemosiderin or lipofuscin
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