General
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• Infection is usually limited to lymph nodes (“bubo”, as in bubonic plague)
• Pneumonic plague occurs if bacterial are aerosolized (eMedicine, Wikipedia)

Micro description
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• Depletion of lymphocytes, edema, necrosis, foamy macrophages
• Bacteria may involve blood vessels

Micro images
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Lymph node medullary necrosis

Positive stains
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• Yersinia immunostain (Am J Clin Pathol 2002;117:205)

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