Yersinia pestis

Lymph nodes - not lymphoma
Infectious / parasitic disorders
Yersinia pestis

Topic Completed: 1 June 2006

Revised: 4 February 2019, last major update June 2006

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Yersinia pestis lymph nodes

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Table of Contents

Definition / general | Microscopic (histologic) description | Positive stains

Cite this page: DePond W. Yersinia pestis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/lymphnodesyersiniapestis.html. Accessed April 6th, 2020.

Definition / general

Infection is usually limited to lymph nodes ("bubo," as in bubonic plague)
Pneumonic plague occurs if bacterial are aerosolized (eMedicine: Plague [Accessed 2 July 2018], Wikipedia: Bubonic Plague [Accessed 2 July 2018])

Microscopic (histologic) description

Depletion of lymphocytes, edema, necrosis, foamy macrophages
Bacteria may involve blood vessels

Positive stains

Yersinia immunostain (Am J Clin Pathol 2002;117:205)