Home   Chapter Home   Jobs   Conferences   Fellowships   Books

Advertisement

Lymphoma - B cell neoplasms

Plasma cell neoplasms

Osteosclerotic myeloma (POEMS syndrome)

Reviewer: Nikhil Sangle, M.D., University of Utah and ARUP Laboratories (see Reviewers page)
Revised: 13 March 2011, last major update March 2011
Copyright: (c) 2001-2011, PathologyOutlines.com, Inc.

Definition
=========================================================================

● Plasma cell myeloma characterized by osteosclerotic changes in the bony trabeculae with associated paratrabecular fibrosis

Clinical features
=========================================================================

● Often a component of POEMS syndrome (polyneuropathy, organomegaly, endocrinopahty, monoclonal gammopathy and skin changes)
● Usually less than 5% plasma cells
● Relation to typical plasma cell myeloma is unknown
● Associated with lymph node changes resembling the plasma cell variant of Castleman’s disease

End of Lymphoma - B cell neoplasms > Plasma cell neoplasms > Osteosclerotic myeloma (POEMS syndrome)

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).