Lymphoma - B cell neoplasms
B cell disorders - general
Reviewer: Nikhil Sangle, M.D., University of Utah and ARUP Laboratories (see Reviewers page)
Revised: 2 February 2011, last major update February 2011
Copyright: (c) 2001-2011, PathologyOutlines.com, Inc.
● Almost always surface immunoglobulin light chain restricted
● Loss of surface membrane immunoglobulin by B cells in extramedullary sites usually indicates lymphoma, but rarely is present with hyperplasia (Am J Clin Pathol 2005;124:143)
● Low grade tumors may have extensive sarcoid-like granulomas (Arch Pathol Lab Med 2000;124:152)
● B cell non-Hodgkin lymphomas rarely are CD2+, but behavior is similar to CD2- tumors; must differentiate from composite B, T cell lymphomas (Am J Clin Path 2001;115:396)
Granulomas in low grade lymphoma
End of Lymphoma - B cell neoplasms > B cell disorders - general
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).