Lymphoma and plasma cell neoplasms
T / NK cell disorders
Nodal CD8+ cytotoxic T-cell lymphoma

Author: Dragos Luca, M.D. (see Authors page)

Revised: 30 March 2017, last major update August 2011

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Nodal CD8+ cytotoxic T cell lymphoma

Cite this page: Nodal CD8+ cytotoxic T-cell lymphoma. website. Accessed July 18th, 2018.
Case reports
Prognosis and treatment
  • Poor prognosis - diffuse large cell type with massive necrosis, apoptosis, DIC or hemophagocytic syndrome (Mod Pathol 2002;15:1131)
  • Better prognosis - diffuse medium or mixed cell type
Postulated normal counterpart
  • CD8 positive cytotoxic T lymphocytes
Microscopic (histologic) images

Images hosted on other servers:

Macrophages ingesting nuclear debris

Diffuse small, medium and large cleaved cells




Granzyme B+


EBER1+ in situ hybridization

Positive stains
Negative stains