Lymphoma - Non B cell neoplasms - Non-B, non-T lymphoblastic lymphoma

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Lymphoma - Non B cell neoplasms

T/NK cell disorders

Non-B, non-T lymphoblastic lymphoma

Reviewer: Dragos Luca, M.D. (see Reviewers page)
Revised: 27 September 2011, last major update September 2011
Copyright: (c) 2001-2011, PathologyOutlines.com, Inc.

Terminology
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● Includes CD7+ stem cell lymphoma (CD7+, CD4-, CD56-, CD33 variable), blastic NK lymphoma (CD56+, CD4-, CD33-, CD123-, CD7 variable, see above), myeloid/NK precursor leukemia (CD4-, CD7+, CD33+, CD56+), CD4+/CD56+ hematodermic malignancy (also CD33-, CD123+, CD7 variable, Am J Surg Pathol 2003;27:1366)
● CD7+ stem cell leukemia: CD7+ but no other lineage marker expressed; frequently presents with mediastinal mass and bone marrow invasion; may convert to AML

Treatment and prognosis
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● May have poorer prognosis than T-cell lymphoblastic lymphoma

Negative stains
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● B-cell markers (CD19, CD20 and CD79a), surface CD3

End of Lymphoma - Non B cell neoplasms > T/NK cell disorders > Non-B, non-T lymphoblastic lymphoma

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