Lymphoma and plasma cell neoplasms
B cell lymphoma subtypes
Primary cutaneous diffuse large B cell lymphoma - Leg

Author: Nikhil Sangle, M.D. (see Authors page)

Revised: 3 April 2017, last major update March 2011

Copyright: (c) 2001-2017,, Inc.

PubMed Search: leg primary cutaneous diffuse large b cell lymphoma

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Cite this page: Primary cutaneous diffuse large B cell lymphoma - Leg. website. Accessed January 22nd, 2019.
Clinical features
Case reports
Clinical images

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Plaque on back

Gross description
  • Solitary or grouped red / blue nodules
Microscopic (histologic) description
  • Dense, diffuse large cells infiltrating entire dermis
  • Cells resemble immunoblasts (large oval vesicular nuclei with prominent nucleoli) or centroblasts (large noncleaved nuclei, prominent nucleoli)
  • Usually thin Grenz zone