Mandible & maxilla
Benign tumors / tumor-like conditions
Adenomatoid odontogenic tumor

Topic Completed: 1 October 2013

Revised: 19 November 2019

Copyright: 2004-2019,, Inc.

PubMed Search: Adenomatoid odontogenic tumor [title]

Nat Pernick, M.D.
Page views in 2018: 3,127
Page views in 2019 to date: 3,409
Cite this page: Pernick N. Benign tumors / tumor-like conditions: adenomatoid odontogenic tumor. website. Accessed December 15th, 2019.
Definition / general
  • Also called adenoameloblastoma
  • Relatively uncommon
  • 70% in teens, remainder from 5 to 50 years, more common in females
  • Associated with unerupted canine tooth
  • Slow growing, few / no symptoms
  • Incisor-cuspid area of maxilla
Radiology description
  • Well defined unilocular lesion surrounding crown of unerupted or impacted tooth
  • May be cystic or expansive but not invasive
Case reports
  • Enucleation; does not recur
Clinical images

Images hosted on other servers:
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Fig 1: solitary cyst-like lesion

Gross description
  • Rounded, well defined fibrous capsule, cystic with focal solid areas
  • Crown of tooth usually projects into cystic cavity
Microscopic (histologic) description
  • Well circumscribed, central proliferation of ductlike epithelium surrounding small foci of calcification
  • Epithelium may have rosettes, trabecular or cribriform patterns
  • Columnar type cells with basal nuclei and clear cytoplasm may resemble pre-ameloblasts
  • Eosinophilic fibrillar material is present between tumor cells and within ductlike structures
  • Rarely melanin deposition
Microscopic (histologic) images

Images hosted on other servers:
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Fig. 2-4: ductlike spaces and solid nodules

Electron microscopy description
  • Glandular differentiation
Differential diagnosis
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