Mandible & maxilla
Benign tumors / tumor-like conditions
Ameloblastic fibroma

Topic Completed: 1 January 2004

Minor changes: 8 July 2020

Copyright: 2004-2018,, Inc.

PubMed Search: Ameloblastic fibroma (mandible OR maxilla)

Nat Pernick, M.D.
Page views in 2019: 3,056
Page views in 2020 to date: 1,984
Cite this page: Pernick N. Ameloblastic fibroma. website. Accessed August 14th, 2020.
Definition / general
  • Rare
  • Usually age 20 or less
  • Benign, rarely recurs
Radiology description
  • Variable radiolucent - radiopaque appearance
  • Simple curettage
Gross description
  • Usually solid
Microscopic (histologic) description
  • Small islands and cords of markedly attenuated ameloblastic epithelium two cells thick within dense collagenous stroma that is often immature
  • Occasional dentin or cementum production and stellate reticulum
  • Also granular cell variant
Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Kelly Magliocca, D.D.S., M.P.H.

AF at scanning magnification

Odontogenic islands

Odontogenic islands with cystic change, within immature mesenchymal stroma

Odontogenic cords within immature mesenchymal stroma

Differential diagnosis
  • Ameloblastoma: no connective tissue stroma, has dentin and enamel
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