Mandible / maxilla
Benign tumors / tumor-like conditions
Ameloblastic fibroma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 19 June 2018, last major update January 2004

Copyright: (c) 2004-2018,, Inc.

PubMed Search: Ameloblastic fibroma (mandible OR maxilla)

Cite this page: Pernick, N. Benign tumors / tumor-like conditions: ameloblastic fibroma. website. Accessed August 16th, 2018.
Definition / general
  • Rare
  • Usually age 20 or less
  • Benign, rarely recurs
Radiology description
  • Variable radiolucent - radiopaque appearance
  • Simple curettage
Gross description
  • Usually solid
Microscopic (histologic) description
  • Small islands and cords of markedly attenuated ameloblastic epithelium two cells thick within dense collagenous stroma that is often immature
  • Occasional dentin or cementum production and stellate reticulum
  • Also granular cell variant
Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by Kelly Magliocca, DDS, MPH

AF at scanning magnification

Odontogenic islands

Odontogenic islands with cystic change, within immature mesenchymal stroma

Odontogenic cords within immature mesenchymal stroma

Differential diagnosis
  • Ameloblastoma: no connective tissue stroma, has dentin and enamel