Other benign / low grade tumors
Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 3 March 2013, last major update December 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Benign tumor, common in kidney, rare in mediastinum
● May arise in setting of tuberous sclerosis complex
● Angiomyolipomas in mediastinum and lung, possibly associated with lymphangioleiomyomatosis and tuberous sclerosis complex
(J Thorac Imaging 2012;27:W21)
● Incidentally discovered angiomyolipoma in the anterior mediastinum (Ann Diagn Pathol 2008;12:293)
Large fatty anterior mediastinal mass
● Composed of varying proportions of smooth muscle cells, blood vessels, and adipose tissue
Confluencing vessel lumina partly filled with blood (right) and interstitial stroma containing mostly smooth muscle cells and focal fat cells
● IHC: positive for smooth muscle actin and HMB-45.
End of Mediastinum > Other benign / low grade tumors > Angiomyolipoma
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