Mediastinum
Cystic lesions
Bronchogenic cyst

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 15 June 2018, last major update December 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Bronchogenic cyst[TI] mediastinum

Cite this page: Gulwani, H. Bronchogenic cyst. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/mediastinumbronchogenic.html. Accessed September 21st, 2018.
Definition / general
  • Due to developmental defect from fusion of tracheoesophageal septum
  • Along tracheobronchial tree, usually posterior to carina
  • Usually asymptomatic
Epidemiology
  • Childhood or middle life
Clinical features
  • Usually symptomatic at diagnosis, complete excision is curative (Lung 2008;186:55)
Radiology description
Xray:
  • Round / oval mass that molds to adjacent structures
  • Wall may contain linear calcifications
  • May have independent vascular supply
Case reports
  • 30 year old man with bronchogenic cyst presenting as a thyroid mass (Head Neck Pathol 2011;5:416)
  • 41 year old woman with carcinoid tumor arising in a thymic bronchogenic cyst associated with thymic follicular hyperplasia (Pathol Int 2012;62:49)
Clinical images

Images hosted on other servers:

Translucent
round cyst behind
descending aorta

Gross description
  • Unilocular or multilocular with internal septation; contain viscous or turbid fluid
Microscopic (histologic) description
  • Resemble normal bronchi
  • Lined by respiratory type epithelium (pseudostratified columnar, often ciliated) with underlying fascicles of smooth muscle and mature cartilage
  • No cholesterol granulomas
  • May have extensive squamous metaplasia
Microscopic (histologic) images

Images hosted on other servers:

Cyst wall with respiratory epithelium

Cyst lining has
pseudostratified
ciliated columnar
epithelium

Bronchial type seromucinous glands beneath epithelium

Differential diagnosis