Mediastinum
Thymic carcinoma
Clear cell thymic carcinoma



Topic Completed: 1 December 2012

Revised: 13 February 2019

Copyright: 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Clear cell thymic carcinoma


Hanni Gulwani, M.B.B.S.
Page views in 2018: 161
Page views in 2019 to date: 248
Cite this page: Gulwani H. Clear cell thymic carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/mediastinumclearcell.html. Accessed September 23rd, 2019.
Definition / general
  • Rare; clear cytoplasm due to either glycogen or degenerative changes
  • Almost always fatal
Case reports
Microscopic (histologic) description
  • Lobular or occasionally sheet-like growth pattern of polygonal cells with clear cytoplasm, rather bland nuclear features, round vesicular nuclei, prominent nucleoli; delicate fibrovascular stroma (Am J Surg Pathol 1995;19:835)
  • No blood lakes, no mucin
Microscopic (histologic) images

Images hosted on other servers:

Large amount of glycogen
rich cytoplasm creates
superficial resemblance
to renal cell carcinoma

Large cells with abundant optically clear cytoplasm

Positive stains
Differential diagnosis
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