Mediastinum
Thymic carcinoma
Clear cell thymic carcinoma

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 19 June 2018, last major update December 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Clear cell thymic carcinoma

Cite this page: Gulwani, H. Clear cell thymic carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/mediastinumclearcell.html. Accessed July 19th, 2018.
Definition / general
  • Rare; clear cytoplasm due to either glycogen or degenerative changes
  • Almost always fatal
Case reports
Microscopic (histologic) description
  • Lobular or occasionally sheet-like growth pattern of polygonal cells with clear cytoplasm, rather bland nuclear features, round vesicular nuclei, prominent nucleoli; delicate fibrovascular stroma (Am J Surg Pathol 1995;19:835)
  • No blood lakes, no mucin
Microscopic (histologic) images

Images hosted on other servers:

Large amount of glycogen
rich cytoplasm creates
superficial resemblance
to renal cell carcinoma

Large cells with abundant optically clear cytoplasm

Positive stains
Differential diagnosis