Mediastinum
Cystic lesions
Seminoma - cystic

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 15 June 2018, last major update December 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Seminoma cystic

Cite this page: Gulwani, H. Seminoma - cystic. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/mediastinumcysticseminoma.html. Accessed September 21st, 2018.
Definition / general
Clinical features
  • Associated with Klinefelter syndrome (XXY), hematologic abnormalities
Case reports
Gross description
  • Variable cystic contents, unilocular or multilocular
Microscopic (histologic) description
  • Seminoma cells present in cyst wall but may not be numerous
  • Have glycogen rich cytoplasm with marked retraction, coarse chromatin with prominent nucleoli, variable mitotic figures
  • Subdivided by fine fibrous trabeculae
  • Associated with germinal centers, giant cells
  • No cholesterol granulomas (may have other granulomas), no cartilage, no smooth muscle
Positive stains