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Mediastinum
Other benign / low grade tumors
Ependymoma
Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 1 March 2013, last major update December 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
General
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● CNS tumor, very rarely occurs as mediastinal primary
Epidemiology
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● Most patients are female
Clinical features
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● Usually do not invade surrounding tissues but lymph node metastases have been reported
● May derive from paravertebral ependymal rests due to location, sympathetic ganglia, lack of teratomatous elements (Ann Diagn Pathol 1998;2:293)
Case reports
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● 39 year old woman with myxopapillary ependymoma of mediastinum (Ann Diagn Pathol 2006;10:283)
● 46 year old woman with primary ependymoma in the posterior mediastinum (Ann Thorac Cardiovasc Surg 2011;17:494)
● 50 year old woman with back pain and cystic tumor (Ann Thorac Cardiovasc Surg 2009;15:332)
● Tumor adherent to the lung with metastasis to adjacent mediastinal lymph nodes (Arch Pathol Lab Med 1988;112:194)
Gross description
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● Tumor shows both cystic and solid elements
Micro images
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End of Mediastinum > Other benign / low grade tumors > Ependymoma
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