Cystic lesions
Pericardial cyst

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 15 June 2018, last major update December 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Pericardial cyst[TIAB] mediastinum

Cite this page: Gulwani, H. Pericardial cyst. website. Accessed July 22nd, 2018.
Definition / general
  • Usually at right cardiophrenic angle, adherent to pericardium and diaphragm; may communicate with pericardial cavity
  • Due to failure of one of multiple disconnected lacunae to merge with the others
Clinical features
  • Usually asymptomatic patients of all ages anywhere in mediastinum; rarely associated with dyspnea or chest pain
Radiology description
  • Xray: irregular, adjacent to cardiac contour
Case reports
Gross description
  • Thin fibrous wall, unilocular, collapses when opened, smooth cyst lining, serous fluid contents
Microscopic (histologic) description
  • Fibrous tissue lined by bland mesothelium, rarely with papillary hyperplasia, no cholesterol granulomas, no smooth muscle, no cartilage, no specialized epithelium
Microscopic (histologic) images

Images hosted on other servers:

Cyst wall composed of
thin layer of fibrous
tissue lined with single
layer of mesothelial cells

Positive stains