Tumors - general
Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 24 March 2013, last major update December 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Extensive variety of tumors possible, encompassing hyperplastic conditions and both benign and malignant neoplasms (Histopathology 2009;54:69)
● Macroscopic invasion into lung, pericardium or vessels is usually associated with the potential for invasive growth, although not necessarily malignancy (thymomas, fibromatosis, fibrosing mediastinitis)
● Hemorrhage and necrosis are usually associated with malignancy
● Encapsulation is associated with indolent processes (benign cysts, thymomas)
● Stromal bands are associated with thymomas (bands intersect at right angles) or lymphoma (bands intersect obliquely)
● Sternberg’s approach to mediastinal tumors: cystic or not, atypical cells or not, if malignant-either small cells, large polygonal cells, mixed small and large polygonal cells, spindle/pleomorphic cells, myxoid-adipose
End of Mediastinum > Tumors > Tumors - general
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