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Molecular markers
Molecular cytology competency assessment
Gene organization and expression




Topic Completed: 1 February 2014

Revised: 4 January 2019, last major update February 2014

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PubMed Search: Gene organization and expression [title] cytopathology review[ptyp]

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Table of Contents
Medical knowledge | Practice based learning and systems based practice
Cite this page: Baloch Z.W. Gene organization and expression. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/molecularcompgeneorg.html. Accessed February 17th, 2019.
Medical knowledge
  1. Describe the human genome (size, composition, designation of specific genetic components and genetic content)
  2. Understand the concept of polymorphism
  3. Understand what constitutes single nucleotide polymorphism
  4. Understand and list the differences between nucleases, endonucleases, ligases and polymerases, including physiologic roles
  5. Understand the role of specific endonuclease as it relates to a specific DNA sequence and what type of "end" is produced
Practice based learning and systems based practice
  1. Understand the different forms of single nucleotide polymorphism and their role in disease
  2. Understand the role of amplified genes in disease and the diseases caused by them
  3. Describe the role of endonucleases, ligases and polymerases in genetic testing
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