Cite this page: Baloch Z.W. Gene organization and expression. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/molecularcompgeneorg.html. Accessed February 17th, 2019.
Medical knowledge
- Describe the human genome (size, composition, designation of specific genetic components and genetic content)
- Understand the concept of polymorphism
- Understand what constitutes single nucleotide polymorphism
- Understand and list the differences between nucleases, endonucleases, ligases and polymerases, including physiologic roles
- Understand the role of specific endonuclease as it relates to a specific DNA sequence and what type of "end" is produced
Practice based learning and systems based practice
- Understand the different forms of single nucleotide polymorphism and their role in disease
- Understand the role of amplified genes in disease and the diseases caused by them
- Describe the role of endonucleases, ligases and polymerases in genetic testing