Molecular markers
Microarray variations
Cellular microarray

Author: Rodney E. Shackelford, D.O., Ph.D. (see Authors page)

Revised: 1 June 2018, last major update July 2010

Copyright: (c) 2008-2018, PathologyOutlines.com, Inc.

PubMed Search: Cellular microarray[TIAB]

Table of Contents
Definition / general
Cite this page: Shackelford, R.E. Cellular microarray. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/molecularpathmicroarraycellular.html. Accessed October 21st, 2018.
Definition / general
  • Cellular microarray uses living cells as a target and solid phase probes, which can consist of nucleic acids, antibodies, lipids, proteins, cytokines or any substance to which the cells being examined may bind
  • Like other microarray assays, the target cells are hybridized to the chip, washed extensively and the binding pattern is analyzed
  • Cell count, cell type capture, cell response or changes in cell morphology / phenotype may be analyzed following different treatments applied to the washed chip (staining, morphologic evaluation, etc.)
  • Interesting variation is done with MHC class I or II spotted chips, which allow the analysis of the MHC binding activities of a cell population