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Molecular Pathology


Considerations in microarray use


Author: Rodney E. Shackelford, DO, Ph.D. (see Reviewers page)

Revised: 3 July 2010, last major update July 2010

Copyright: (c) 2008-2010, PathologyOutlines.com, Inc.




A researcher should ask if microarray technology is really necessary for a specific research application, because:

- Microarray is time-consuming and slow to setup, difficult to validate, expensive and requires great analytical expertise

- Microarray can give an enormous amount of irrelevant data

- An available chip may already have the desired set of gene sequences

- Multiplex PCR or a custom chip may be a better method of analysis than employing a genome-wide array


End of Molecular Pathology > Microarray > Considerations in microarray use



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