Chronic Myeloid Neoplasms - WHO classification of myeloproliferative neoplasms

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Chronic Myeloid Neoplasms

Myeloproliferative neoplasms (MPN)

WHO classification of myeloproliferative neoplasms

Reviewer: Nikhil Sangle, M.D. (see Reviewers page)
Revised: 11 August 2011, last major update August 2011
Copyright: (c) 2001-2011, PathologyOutlines.com, Inc.

WHO 2008 - Myeloproliferative neoplasms (MPN)

General
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● Chronic myelogenous leukemia
● Polycythemia vera
● Essential thrombocythemia
● Primary myelofibrosis
● Chronic neutrophilic leukemia
● Chronic eosinophilic leukemia, not otherwise categorized
● Mast cell disease
● MPNs, unclassifiable

WHO 2001 - Chronic myeloproliferative diseases

Definition
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● Chronic myelogenous leukemia (Philadelphia chromosome, t(9;22)(q34;q11), BCR-ABL positive)
● Chronic neutrophilic leukemia
● Chronic eosinophilic leukemia (and the hypereosinophilic syndrome)
● Polycythemia vera
● Chronic idiopathic myelofibrosis (with extramedullary hematopoiesis)
● Essential thrombocythemia
● Chronic myeloproliferative disease, unclassifiable

Additional references
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● Leukemia 2008;22:14 (WHO 2008), Blood 2007;110:1092, Blood 2002;100:2292 (WHO 2001)

End of Chronic Myeloid Neoplasms > Myeloproliferative neoplasms (MPN) > WHO classification of myeloproliferative neoplasms

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