Nasal cavity, paranasal sinuses, nasopharynx
Other tumors
Aneurysmal bone cyst

Author: Abul Ala Syed Rifat Mannan, M.D. (see Authors page)
Editor: Songyang Yuan, M.D., Ph.D.

Revised: 22 May 2018, last major update May 2014

Copyright: (c) 2004-2018,, Inc.

PubMed Search: Aneurysmal bone cyst nasal

Page views in 2018: 217
Page views in 2019 to date: 23
Cite this page: Mannan, A.A.S.R. Aneurysmal bone cyst. website. Accessed January 23rd, 2019.
Definition / general
  • Expansile osteolytic lesion with blood filled spaces separated by fibrous septa containing osteoclast type giant cells and reactive bone
  • For detailed discussion refer to Bone - aneurysmal bone cyst
  • Extremely rare in the sinonasal region, with minimal epidemiologic data
  • Can be associated with fibrous dysplasia
  • No known etiologic associations
  • May be localized to the sinuses or involve other nasal bones
Radiology images

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CT scans of tumor

Axial T2 of skull base

Case reports
Clinical images

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Endoscopic view of left nostril

Microscopic (histologic) description
  • Microscopic features are similar to aneurysmal bone cyst occurring elsewhere in the body
  • Spindled, ovoid or round histiocytes-like cells in well vascularized fibrous stroma
  • Cells have 1 - 3 nuclei and may form giant cells with 10 - 20 nuclei that aggregate in groups of 6 - 12 cells
  • Giant cells tend to invade and line vascular channels
  • Lesions contain metaplastic woven bone and lamellar bone lined by osteoblasts and occasionally osteoclasts
  • Prominent extravasation of blood, numerous mitotic figures
Microscopic (histologic) images

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Fibrous dysplasia

Aneurysmal bone cyst