Nasal cavity, paranasal sinuses, nasopharynx
Borderline / low grade soft tissue tumors
Solitary fibrous tumor

Topic Completed: 1 November 2004

Revised: 5 June 2019

Copyright: 2004-2019,, Inc.

PubMed Search: Solitary fibrous tumor nasal

Nat Pernick, M.D.
Page views in 2018: 816
Page views in 2019 to date: 497
Cite this page: Pernick N. Solitary fibrous tumor. website. Accessed July 23rd, 2019.
Definition / general
  • Uncommon, resembles pleural tumor
  • Closely related to hemangiopericytoma of soft tissues
  • Intranasal extension and erosion of adjacent structures is common but tumors do not metastasize
  • Usually ages 40+ years, no gender preference
Case reports
  • Local excision
Gross description
  • Polypoid mass
  • Yellow-tan with smooth surface
  • Pink-tan homogenous cut surface
Microscopic (histologic) description
  • Nonencapsulated
  • Patternless proliferation of bland spindled fibroblasts in collagenous background (ropey keloidal collagen), prominent blood vessels resemble hemangiopericytoma but have thin walls
  • Hyper and hypocellular areas
  • Rare mitotic figures
Microscopic (histologic) images

Images hosted on other servers:

Fig 1: tumor with overlying nasal mucosa
Fig 2: cellular area composed of bland spindle cells
Fig 3 / 4: bland spindle cells mixed with disrupted collagen
Fig 5: CD34+

Positive stains
Differential diagnosis
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