Nasal cavity, paranasal sinuses, nasopharynx
Other tumors
Solitary fibrous tumor

Author: Nat Pernick, M.D. (see Authors page)

Revised: 25 May 2018, last major update November 2004

Copyright: (c) 2004-2018,, Inc.

PubMed Search: Solitary fibrous tumor nasal

Cite this page: Pernick, N. Solitary fibrous tumor. website. Accessed November 21st, 2018.
Definition / general
  • Uncommon, resembles pleural tumor
  • Closely related to hemangiopericytoma of soft tissues
  • Intranasal extension and erosion of adjacent structures is common but tumors do not metastasize
  • Usually ages 40+ years, no gender preference
Case reports
  • Local excision
Gross description
  • Polypoid mass
  • Yellow-tan with smooth surface
  • Pink-tan homogenous cut surface
Microscopic (histologic) description
  • Nonencapsulated
  • Patternless proliferation of bland spindled fibroblasts in collagenous background (ropey keloidal collagen), prominent blood vessels resemble hemangiopericytoma but have thin walls
  • Hyper and hypocellular areas
  • Rare mitotic figures
Microscopic (histologic) images

Images hosted on other servers:

Fig 1: tumor with overlying nasal mucosa
Fig 2: cellular area composed of bland spindle cells
Fig 3 / 4: bland spindle cells mixed with disrupted collagen
Fig 5: CD34+

Positive stains
Differential diagnosis