Nasal cavity, paranasal sinuses, nasopharynx
Other tumors

Author: Abul Ala Syed Rifat Mannan, M.D. (see Authors page)
Editor: Songyang Yuan, M.D., Ph.D.

Revised: 22 May 2018, last major update April 2014

Copyright: (c) 2004-2018,, Inc.

PubMed Search: Ameloblastoma nasal

Cite this page: Mannan, A.A.S.R. Ameloblastoma. website. Accessed November 18th, 2018.
Definition / general
  • Rare tumor of sinonasal tract
  • Most tumors at this site secondarily involve the sinonasal tract by extension from the maxilla
  • True primary sinonasal ameloblastoma, without connection to gnathic sites, is extremely rare (Cancer 1998;82:667)
  • More common in elderly men, with mean age at presentation of 59.7 years
  • Most common site is maxillary sinus
  • Can involve exclusively the nasal cavity or sinuses or both
  • No known etiologic associations
  • Most common presenting symptoms are mass lesion and nasal obstruction
Radiology description
  • Usually presents as solid opacification, in contrast to characteristic multilocular and radiolucent presentation of gnathic ameloblastoma
Radiology images

Images hosted on other servers:

Various images

Soft tissue polypoidal mass

Soft tissue mass

Large lytic expansile, solid lesion

Prognostic factors
  • Slow growing tumor that may recur locally
  • No tumor related deaths, metastasis or malignant transformation reported
Case reports
  • Complete surgical excision is treatment of choice
Clinical images

Images hosted on other servers:

Alveolar swelling in buccal aspect

Tumor of upper nasal septum

Microscopic (histologic) description
  • Histologically similar to counterpart in gnathic region - see Mandible / maxilla chapter
Microscopic (histologic) images

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Islands of odontogenic epithelium

Cords and follicular islands

Classic basaloid appearance

Collagenized stroma


CK AE1 / AE3

Contributed by Songyang Yuan, M.D., Ph.D.

Tumor is composed of proliferating nests of columnar tumor cells arranged in a palisading pattern