Nasal cavity, paranasal sinuses, nasopharynx
Inflammatory / infectious lesions

Author: Nat Pernick, M.D. (see Authors page)

Revised: 16 May 2018, last major update November 2004

Copyright: (c) 2004-2018,, Inc.

PubMed Search: Aspergillus nasal cavity

Cite this page: Pernick, N. Aspergillus. website. Accessed November 18th, 2018.
Definition / general
  • Causes fungus balls in nasal antrum of immunocompetent patients with minimal inflammatory response, microabscesses or multinucleated giant cells
  • Also causes invasive aspergillosis, regardless of immune status, with extension into retroorbital region, cranium or parapharyngeal space; often fatal
  • Also causes allergic fungal sinusitis
Microscopic (histologic) description
  • Septate hyphae that branch at 45 degrees
Differential diagnosis
Of fungal infections:
  • Alternaria
  • Cladosporium trichoides
  • Fusarium
  • Paecilomyces
  • Pseudallescheria boydii
  • Zygomycetes