Nasal cavity, paranasal sinuses, nasopharynx
Benign / nonneoplastic lesions: mesenchymal
Nasal chondromesenchymal hamartoma


Topic Completed: 1 August 2004

Minor changes: 2 March 2020

Copyright: 2004-2020, PathologyOutlines.com, Inc.

PubMed Search: Nasal chondromesenchymal hamartoma

Nat Pernick, M.D.
Page views in 2019: 1,547
Page views in 2020 to date: 765
Cite this page: Pernick N. Nasal chondromesenchymal hamartoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/nasalchondromes.html. Accessed May 28th, 2020.
Definition / general
  • Rare; intranasal and paranasal polypoid mass in infants and occasionally older children
  • 2/3 male, mean age 14 months, range 1 day to 7 years
  • Benign but fills nasal cavity and usually extends into ethmoid sinuses
  • May erode bone, including cribriform plate and have an intracranial component
Radiology images

Contributed by Dr. I Weng Lao and Dr. Jian Wang, Fudan University Shanghai Cancer Center (China):

CT scan



Images hosted on other servers:

Tumor with cystic component

Case reports
Treatment
  • Excision
Microscopic (histologic) description
  • Well demarcated mature cartilage, myxoid stroma, focal osteoclast-like giant cells, aneurysmal bone cyst-like formations, spindle cells, collagen fibers
Microscopic (histologic) images


Contributed by Dr. I Weng Lao and Dr. Jian Wang, Fudan University Shanghai Cancer Center (China):

Various images



Case of the Week #291:

Various images



Images hosted on other servers:

Lobules of cartilage and spindle cells

Reactive bone resembling fibrous dysplasia


Positive stains
Electron microscopy description
  • Fibroblastic and myofibroblastic differentiation
Electron microscopy images

Images hosted on other servers:

Loose bundles of microfilaments

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