Nasal cavity, paranasal sinuses, nasopharynx
Other tumors
Nasal chondromesenchymal hamartoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 23 May 2018, last major update August 2004

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Nasal chondromesenchymal hamartoma

Cite this page: Pernick, N. Nasal chondromesenchymal hamartoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/nasalchondromes.html. Accessed July 18th, 2018.
Definition / general
  • Rare; intranasal and paranasal polypoid mass in infants and occasionally older children
  • 2/3 male, mean age 14 months, range 1 day to 7 years
  • Benign but fills nasal cavity and usually extends into ethmoid sinuses
  • May erode bone, including cribriform plate and have an intracranial component
Radiology images

Images hosted on other servers:

Tumor with cystic component



Contributed by Dr. I Weng Lao and Dr. Jian Wang, Fudan University Shanghai Cancer Center (China):

CT scan

Case reports
Treatment
  • Excision
Microscopic (histologic) description
  • Well demarcated mature cartilage, myxoid stroma, focal osteoclast-like giant cells, aneurysmal bone cyst-like formations, spindle cells, collagen fibers
Microscopic (histologic) images

Images hosted on PathOut server:

Case of the Week #291:

Various images



Images hosted on other servers:

Lobules of cartilage and spindle cells

Reactive bone resembling fibrous dysplasia



Contributed by Dr. I Weng Lao and Dr. Jian Wang, Fudan University Shanghai Cancer Center (China):

Various images

Positive stains
Electron microscopy description
  • Fibroblastic and myofibroblastic differentiation
Electron microscopy images

Images hosted on other servers:

Loose bundles of microfilaments