Nasal cavity, paranasal sinuses, nasopharynx
Other malignant tumors
Chordoma


Topic Completed: 1 September 2014

Minor changes: 8 October 2020

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PubMed Search: Chordoma[TI] nasal

See also: Bone chapter

Rifat Mannan, M.D.
Songyang Yuan, M.D., Ph.D.
Page views in 2019: 747
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Cite this page: Mannan R, Yuan S. Chordoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/nasalchordoma.html. Accessed November 30th, 2020.
Definition / general
  • Malignant nonepithelial neoplasm derived from notochordal tissue
  • Primary chordomas are extremely rare in nasal cavity and paranasal sinuses
  • Clival chordomas may present as a nasal mass by anterior extension
Radiology images

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Chordoma in nasal cavity

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Chordoma in nasopharynx

Case reports
Microscopic (histologic) description
  • Physaliphorous cells with multiple cytoplasmic vacuoles within myxoid stroma
  • No glandular formation
  • Chondroid variants contain cartilage
Negative stains
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