Nasal cavity, paranasal sinuses, nasopharynx

Topic Completed: 1 September 2014

Revised: 5 June 2019

Copyright: 2004-2019,, Inc.

PubMed Search: Chordoma[TI] nasal

See also: Bone chapter

Rifat Mannan, M.D.
Songyang Yuan, M.D., Ph.D.
Page views in 2018: 611
Page views in 2019 to date: 695
Cite this page: Mannan R, Yuan S. Chordoma. website. Accessed December 5th, 2019.
Definition / general
  • Malignant nonepithelial neoplasm derived from notochordal tissue
  • Primary chordomas are extremely rare in nasal cavity and paranasal sinuses
  • Clival chordomas may present as a nasal mass by anterior extension
Radiology images

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Chordoma in nasal cavity

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Chordoma in nasopharynx

Case reports
Microscopic (histologic) description
  • Physaliphorous cells with multiple cytoplasmic vacuoles within myxoid stroma
  • No glandular formation
  • Chondroid variants contain cartilage
Microscopic (histologic) images

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Classical chordoma, nonnasal

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Variants of chordoma, nonnasal

Negative stains
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