Nasal cavity, paranasal sinuses, nasopharynx
Other tumors
Craniopharyngioma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 24 May 2018, last major update November 2004

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Craniopharyngioma[TI] nasal

Cite this page: Pernick, N. Craniopharyngioma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/nasalcraniopharyngioma.html. Accessed July 16th, 2018.
Definition / general
  • Rarely occurs as nasopharyngeal or sphenoid sinus lesion
  • Benign epithelial tumor of central nervous system, usually in sellar and suprasellar areas
  • Often recurs after excision, rarely undergoes malignant change
  • Either ages 0 - 20 or 60+ years
  • Slow growing, often large when detected
Case reports
Microscopic (histologic) images

Images hosted on other servers:

Fig 2: adamantinomatous craniopharyngioma consisting of trabeculae with palisading basal layer surrounding loosely cohesive squamous cells and keratin nodules
Fig 3: squamous cell carcinoma
Fig 4: squamous cells separated by stellate reticulum transforming to adjacent squamous cell carcinoma (left)
Fig 5: p53+ squamous cell carcinoma (top) vs. p53- craniopharyngioma (bottom)