Nasal cavity, paranasal sinuses, nasopharynx
Other tumors

Author: Nat Pernick, M.D. (see Authors page)

Revised: 23 May 2018, last major update November 2004

Copyright: (c) 2004-2018,, Inc.

PubMed Search: Fibromatosis[TI] nasal

Cite this page: Pernick, N. Fibromatosis. website. Accessed September 21st, 2018.
Definition / general
  • 12% of fibromatosis cases involve head and neck
  • All ages, no gender preference
  • Recurs locally, particularly after incomplete excision, which is common in this region
  • Doesn't metastasize; rarely regresses in children with multiple fibromatosis
  • May be component of Gardner syndrome
Gross description
  • Firm fibrous mass with infiltrative margins
Microscopic (histologic) description
  • Broad fascicles and bundles of well differentiated fibroblasts and myofibroblasts with collagenous fibrous tissue
  • May be storiform but no herringbone pattern
  • Cells have uniform nuclei with sharply pointed ends in cross section, dense chromatin, no nucleoli, rare mitotic figures
  • Infiltrates surrounding tissue
Differential diagnosis