Nasal cavity, paranasal sinuses, nasopharynx
Hematologic conditions
Follicular lymphoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 22 May 2018, last major update November 2004

Copyright: (c) 2004-2018,, Inc.

PubMed Search: Follicular lymphoma nasal

Cite this page: Pernick, N. Follicular lymphoma. website. Accessed November 21st, 2018.
Definition / general
  • In children, 75% male, usually localized disease, no bone marrow involvement, often in nasopharynx, excellent prognosis
Microscopic (histologic) description
  • Usually centroblast predominant (grade 3 of 3) with high mitotic rate
  • May have plasmacytoid differentiation
Positive stains
  • Monoclonal light chain expression, BCL6
Negative stains
Molecular / cytogenetics description
  • Usually no BCL2 gene rearrangements but monoclonal
Differential diagnosis