Nasal cavity, paranasal sinuses, nasopharynx
Inflammatory / idiopathic / autoimmune

Topic Completed: 1 November 2004

Revised: 30 May 2019

Copyright: 2004-2019,, Inc.

PubMed Search: Myospherulosis nasal

Nat Pernick, M.D.
Page views in 2018: 503
Page views in 2019 to date: 261
Cite this page: Pernick N. Myospherulosis. website. Accessed June 17th, 2019.
Definition / general
  • Iatrogenic lipogranuloma after hemostatic packing of nasal cavity or paranasal sinuses with petrolatum based ointment and gauze
  • Resembles subcutaneous disease of East Africa
Microscopic (histologic) description
  • Large tissue spaces with sac-like structures containing brown spherules resembling Prototheca but actually clumped red blood cells
Negative stains
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