Nasal cavity, paranasal sinuses, nasopharynx
Inflammatory / infectious lesions
Pertussis

Author: Nat Pernick, M.D. (see Authors page)

Revised: 18 May 2018, last major update November 2004

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Pertussis[TI] nasal

Cite this page: Pernick, N. Pertussis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/nasalpertussis.html. Accessed October 19th, 2018.
Definition / general
  • Possibly life threatening nasopharyngeal infection caused by Bordetella pertussis
  • Causes progressive, repetitive paroxysmal coughing, mild systemic complaints and lymphocytosis
  • Worldwide causes 60 million severe cases and 1 million deaths annually
  • In U.S., 5,000 - 7,000 annual cases, deaths usually only in infants younger than 1 year
  • Outbreak in Wisconsin (U.S.) in 1993 with attack rates of 23% (ages 30 - 49 years) and 33% (ages 50+)
  • Vaccination widely given but efficacy may wane 4 years after last dose
Diagnosis
  • Culture requires 5 - 7 days, also PCR
Treatment
  • Erythromycin (but some cases are resistant)
Additional references