Nasal cavity, paranasal sinuses, nasopharynx
Inflammatory / infectious lesions
Nasal polyps, angiectatic

Topic Completed: 1 November 2004

Revised: 25 April 2019

Copyright: 2004-2019,, Inc.

See also: General, Antrochoanal, Atypical stromal cells, Cystic fibrosis, Inflammatory

Nat Pernick, M.D.
Page views in 2018: 1,706
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Cite this page: Pernick N Nasal polyps, angiectatic. website. Accessed August 18th, 2019.
Definition / general
  • Extensive vascular proliferation and ectasia with pseudoamyloid deposition that simulates malignancy
  • Due to marked reactive and reparative changes
  • May cause life threatening epistaxis, facial deformity or bone erosion and remodeling
Gross description
  • Gelatinous, semitranslucent masses with smooth, blue-gray glistening surface
Gross images

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Marked hemorrhage and spongiform change

Microscopic (histologic) description
  • Dilated thin walled vessels in pools of eosinophilic material, associated with patchy necrosis and atypical spindle cells
  • Associated with choanal polyps arising in paranasal sinuses and protruding into nasopharynx
Microscopic (histologic) images

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Proliferation of thin walled vascular channels

Thin walled vessels in amorphous material

Atypical stromal cells and fibrin thrombi

Vascular channels
lined by large
endothelial cells

Electron microscopy images

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Poorly formed vascular channel

Differential diagnosis
Additional references
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