Nasal cavity, paranasal sinuses, nasopharynx
Other tumors

Author: Nat Pernick, M.D. (see Authors page)

Revised: 25 May 2018, last major update November 2004

Copyright: (c) 2004-2018,, Inc.

PubMed Search: Schwannoma[TI] nasal[TI]

Cite this page: Pernick, N. Schwannoma. website. Accessed November 18th, 2018.
Definition / general
  • Very rare
  • May be very cellular
  • In one study, 3 of 5 cases were in ethmoid sinus
  • Conservative surgical resection
  • No recurrence or metastases
Gross description
  • Pedunculated or polypoid, white-yellow, 2 - 4 cm
  • No nerve identified
Microscopic (histologic) description
  • No encapsulation
  • Elongated spindle cells in fascicles with poorly defined cytoplasm, oval nuclei with tapering ends, focal nuclear palisading
  • Overlying epithelium may be ulcerated
  • Abundant vasculature
  • Variable Verocay bodies, Antoni A and B patterns
  • No cytologic atypia, low mitotic rate
Microscopic (histologic) images

Images hosted on other servers:

Fig 1: fascicles of elongated spindle cells without atypia
Fig 2: Verocay bodies
Fig 3: poorly demarcated tumor borders with occasional epithelial ulceration
Fig 4: S100; fig 5: low Ki67 / MIB1 staining

Positive stains
Negative stains
Differential diagnosis
Additional references