Oral cavity
Aphthous ulcers

Author: Patricia DeVilliers, DDS, MS, Charu Thakral, M.D. (see Authors page)

Revised: 13 April 2018, last major update June 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Aphthous ulcers[TI] oral cavity

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Cite this page: DeVilliers, P., Thakral, C. Aphthous ulcers. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavityaphthous.html. Accessed January 19th, 2019.
Definition / general
  • Also called canker sores
  • Affect 40% in U.S.
  • More common up to 20 years
  • Painful, recurrent and familial
Case reports
  • Symptomatic
Clinical images

Images hosted on other servers:

Aphthous ulcers

26 year old man:

Minor ulcer

Major ulcer

Laser therapy

After one week of laser treatment

Gross description
  • Single or multiple, shallow, hyperemic ulcerations covered by a thin exudate with hyperemic rim
Microscopic (histologic) description
  • Initially mononuclear infiltrate, then neutrophilic infiltrate from secondary bacterial infection