Oral cavity
Minor salivary gland tumors / lesions
Choristoma

Author: Nella Cristina Fernandez, M.D. (see Authors page)

Revised: 27 April 2018, last major update August 2013

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Choristoma minor salivary glands

Cite this page: Fernandez, N.C. Choristoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitychoristoma.html. Accessed December 14th, 2018.
Definition / general
  • Choristoma is a tumor-like mass consisting of normal cells in an abnormal location (J Oral Maxillofac Surg 2012;24:110)
  • Hamartoma is a tumor-like malformation composed of mature normal cells in usual location but as a disorganized mass
Epidemiology
Sites
  • 85% of osseous and cartilaginous choristomas occur on tongue (dorsal posterior third near foramen cecum)
Clinical features
  • Firm, exophytic, asymptomatic nodule covered by intact oral mucosa
  • Base may be sessile or pedunculated
Case reports
Treatment
  • Surgical excision
Clinical images

Images hosted on other servers:

Osseous choristoma

Gross description
Gross images

Images hosted on other servers:

Osseous choristoma

Microscopic (histologic) description
  • Oral choristomas can be classified according to types of tissues they constitute (J Oral Maxillofac Surg 2012;24:110):
    1. Salivary gland choristoma
      1. Central
      2. Gingival
      3. Both have ectopic salivary gland tissue appearing as a raised tumor-like mass; must not have any connection with normal minor or major salivary glands
    2. Cartilagenous choristoma: composed of mature hyaline cartilage in fibrous tissue that resembles perichondrium; usually multilobulated; chondrocytes vary from small to large but lack atypia
    3. Osseous choristoma: composed of dense mature bone; osteocytes are compact and unremarkable; no prominent osteoblastic rimming; occasionally bone and cartilage are present in same lesion
    4. Lingual thyroid choristoma
    5. Lingual sebaceous choristoma
    6. Glial choristoma
    7. Gastric / respiratory mucosal choristoma
      1. Solid
      2. Cystic
Microscopic (histologic) images

Images hosted on other servers:

Osseous choristoma

Differential diagnosis
  • Cartilaginous metaplasia: usually occurs in soft tissue beneath ill fitting dentures, has diffuse deposits of calcium, scattered cartilaginous cells arranged in various stages of maturation in single or clustered foci
  • Pleomorphic adenoma: may have osteocartilaginous foci
  • Salivary gland tissue: choristomas lack salivary gland ductal or myoepithelial components