Table of ContentsDefinition / general | Clinical images | Microscopic (histologic) description | Microscopic (histologic) images
Cite this page: Thakral, C. Crohn's disease. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitycrohns.html. Accessed January 19th, 2019.
Definition / general
- Initial presentation may be in oral cavity and pharynx
- 6% have oral lesions at some time (lip, gingiva, vestibular sulci, buccal mucosa)
- Pyostomatitis vegetans: rare oral lesion associated with inflammatory bowel disease that may precede intestinal involvement; characterized by erythematous, thickened oral mucosa with multiple pustules and superficial erosions; usually peripheral eosinophilia
Microscopic (histologic) description
- Edema, ulcers, papillary hyperplastic mucosa, dilation of lymphatics, chronic inflammatory infiltrate, giant cells and rarely noncaseating granulomas