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Table of Contents
Definition / general | Case reports | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Negative stains | Electron microscopy descriptionCite this page: Thakral C Crystal storing histiocytosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitycrystalhistiocytosis.html. Accessed March 25th, 2019.
Definition / general
- Rare; crystalline material accumulates in cytoplasm of histiocytes; usually kappa light chain origin
- Typically associated with disorders that express monoclonal immunoglobulins such as myeloma, lymphoplasmacytic lymphoma, monoclonal gammopathy of undetermined significance
Case reports
- 51 year old woman with upper lip and cheek tumor (Head Neck Pathol 2012;6:111)
- 73 year old woman with tongue mass, chronic rheumatoid arthritis, polyclonal hypergammaglobulinemia (Arch Pathol Lab Med 1998;122:920)
Microscopic (histologic) description
- Histiocytes filled with nonbirefringent eosinophilic crystals
- Lymphocytes and plasma cells also present
Microscopic (histologic) images
Images hosted on other servers:
Eosinophilic histiocytes
CD68+
Immunoglobulin stains
Positive stains
Negative stains
Electron microscopy description
Images hosted on other servers:
Dense crystals
