Oral cavity
Infectious
Diphtheria

Author: Patricia DeVilliers, DDS, MS, Charu Thakral, M.D. (see Authors page)

Revised: 16 April 2018, last major update June 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Diphtheria oral cavity

Cite this page: DeVilliers, P., Thakral, C. Diphtheria. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitydiphtheria.html. Accessed July 22nd, 2018.
Definition / general
  • Upper respiratory tract illness caused by Corynebacterium diphtheriae, a facultative anaerobic and Gram positive bacterium
  • Characterized by sore throat, low fever and an adherent membrane (pseudomembrane) on tonsils, pharynx, nasal cavity
  • May lead to myocarditis (20%), neuropathy (10%)
  • Diphtheria, pertussis and tetanus (DPT) vaccine recommended for all school age children in U.S.
Drawings

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False membrane extends to soft palate

Clinical images

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Skin lesions

"Bull neck"


McLoed agar plate culture

Blood agar culture

Cystine tellurite plate culture

Gross description
  • Dirty white, fibrinosuppurative, tough, inflammatory membrane over tonsils and posterior pharynx
Microscopic (histologic) images

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Gram positive bacteria