Reviewer: Patricia DeVilliers, D.D.S., M.S., Charu Thakral, M.D. (see Reviewers page)
Revised: 19 June 2013, last major update June 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
- Upper respiratory tract illness caused by Corynebacterium diphtheriae, a facultative anaerobic and Gram positive bacterium
- Characterized by sore throat, low fever and an adherent membrane (pseudomembrane) on tonsils, pharynx, nasal cavity
- May lead to myocarditis (20%), neuropathy (10%)
- Diphtheria-pertussis-tetanus (DPT) vaccine recommended for all school-age children in U.S.
False membrane extends to soft palate
- Dirty white, fibrinosuppurative, tough, inflammatory membrane over tonsils and posterior pharynx
McLoed’s agar plate culture
Blood agar culture
Cystine tellurite plate culture
End of Oral cavity > Infectious > Diphtheria
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