Table of Contents
Definition / general | Case reports | Clinical images | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosisCite this page: Thakral C. Ephelis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/oralcavityephelis.html. Accessed March 28th, 2024.
Definition / general
- Also called freckle
- Solitary melanotic macules, usually of lower lip
- More common in women; associated with Peutz-Jeghers syndrome
Case reports
- 4 patients with labial melanotic macule (Dermatology 2012;224:209)
Clinical images
Microscopic (histologic) description
- Hyperpigmentation of basal layer with elongation of rete ridges
Differential diagnosis
- Melanoacanthoma:
- Melanocytes mixed with keratinocytes
- Melanosis:
- Pigmented patches in hard palate or gingiva