Oral cavity
Congenital anomalies
Epithelial nests

Author: Charu Thakral, M.D. (see Authors page)

Revised: 13 April 2018, last major update January 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Epithelial nests oral cavity

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Cite this page: Thakral, C. Epithelial nests. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavityepithelialnests.html. Accessed January 20th, 2019.
Definition / general
  • Not actually a congenital anomaly but normal occurring neuroepithelial structure called organ of Chievitz, Chievitz paraparotid organ or juxtaoral organ
  • Reported in 56% of adult autopsies without oral mucosal lesions
  • Within intraoral sensory nerve
  • May undergo nodular hyperplasia
  • Located bilaterally in buccotemporal fascia on medial surface of mandible, near angle
  • Rare examples of proliferative / hamartomatous masses of juxtaoral organ reported
  • May be interpreted as squamous cell carcinoma, mucoepidermoid carcinoma or metastasis especially during frozen sections (Am J Surg Pathol 1979;3:147)
Case reports
Microscopic (histologic) description
  • Multilobulated nests of squamous-like epithelium without keratin formation, occasionally with lumen lined by cuboidal cells
  • Associated with small nerves and resembling perineural invasion
Microscopic (histologic) images

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Nodular hyperplastic nest of juxtaoral organ (B)