Fordyce’s disease / granules
Reviewer: Charu Thakral, M.D. (see Reviewers page)
Revised: 15 June 2013, last major update January 2013
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
- Common; ectopic sebaceous glands within oral cavity (Ann Dermatol 2012;24:103)
- May be hyperplastic and nodular
- Appear as rice-like, yellow-white, asymptomatic 1-3 mm papules that remain constant throughout life
- Neoplastic transformation very rare, but reported; association with HNPCC also reported (Gut 2005;54:1279)
- Buccal mucosa (often bilateral), upper lip vermilion border, mandibular retromolar pad and tonsillar areas
- Similar to normal sebaceous glands of skin, but lack hair follicles and almost always lack ductal communication with surface
Sebaceous glands in dermis of lip
End of Oral cavity > Congenital anomalies > Fordyce’s disease / granules
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