Oral cavity
Inflammatory (noninfectious) lesions
Granulomatous inflammation

Topic Completed: 1 February 2013

Revised: 31 January 2019

Copyright: (c) 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Granulomatous inflammation oral cavity

Charu Thakral, M.D.
Page views in 2018: 860
Page views in 2019 to date: 761
Cite this page: Thakral C Granulomatous inflammation. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitygranulomatousinflamm.html. Accessed September 19th, 2019.
Definition / general
  • Associated with chronic recurrent tonsillitis
  • Usually benign course, no specific organism recovered
  • Must rule out infectious causes (tuberculosis, tertiary syphilis, salmonella, mycotic granulomas), systemic causes (sarcoidosis, Crohn's, Granulomatosis with polyangiitis (Wegener's), eosinophilic granuloma), foreign body reaction, cholesterol granuloma
  • Idiopathic orofacial granulomatosis: condition restricted to oral and maxillofacial region without any identifiable systemic granulomatous disease
Case reports
  • Individualized and often needs to change for each patient; includes corticosteroids or other drugs, gingivectomy
Clinical images

Images hosted on other servers:

9 year old girl:


1 year follow up

11 year old boy:


After 3 months

Microscopic (histologic) images

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Multiple granulomas

Lip and gingival biopsies

Granulomatous lesion and infiltrates

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