Oral cavity
Inflammatory (noninfectious) lesions
Granulomatous inflammation

Author: Charu Thakral, M.D. (see Authors page)

Revised: 17 April 2018, last major update February 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Granulomatous inflammation oral cavity

Cite this page: Thakral, C. Granulomatous inflammation. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitygranulomatousinflamm.html. Accessed August 17th, 2018.
Definition / general
  • Associated with chronic recurrent tonsillitis
  • Usually benign course, no specific organism recovered
  • Must rule out infectious causes (tuberculosis, tertiary syphilis, salmonella, mycotic granulomas), systemic causes (sarcoidosis, Crohn's, Wegener granulomatosis, eosinophilic granuloma), foreign body reaction, cholesterol granuloma
  • Idiopathic orofacial granulomatosis: condition restricted to oral and maxillofacial region without any identifiable systemic granulomatous disease
Case reports
Treatment
  • Individualized and often needs to change for each patient; includes corticosteroids or other drugs, gingivectomy
Clinical images

Images hosted on other servers:

9 year old girl:

Preoperative

1 year follow up


11 year old boy:

Preoperative

After 3 months

Microscopic (histologic) images

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Multiple granulomas

Lip and gingival biopsies

Granulomatous lesion and infiltrates