Oral cavity
Inflammatory (noninfectious) lesions
Hyaline ring-like structures

Author: Charu Thakral, M.D. (see Authors page)

Revised: 17 April 2018, last major update February 2013

Copyright: (c) 2002-2018, PathologyOutlines.com, Inc.

PubMed Search: Hyaline ring-like structures

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Cite this page: Thakral, C. Hyaline ring-like structures. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavityhyalineringlikestructures.html. Accessed January 24th, 2019.
Definition / general
  • Rarely associated with chronic periostitis, edentulous patients
  • May be a degenerative change in vessel walls from vasculitis or a reaction to legume cells at various stages of digestion
  • Central lesions are asymptomatic, peripheral lesions present as painless submucosal swellings
  • Also called pulse granuloma (pulse is edible seed of legumes), oral vegetable granuloma, giant cell hyaline angiopathy
Case reports
  • Excision or curettage
Clinical images

Images hosted on other servers:

Ulcero-proliferative growth

Microscopic (histologic) description
  • Hyaline ring-like structures, some containing granular necrotic material that surrounds giant cells, vessels, collagen and is itself surrounded by chronic inflammatory cells
Microscopic (histologic) images

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Granuloma with eosinophilic ulcer

Muscle cells

Foreign body giant cell

Eosinophilic vegetable matter in cyst

PAS+, Alcian blue+

Vegetable matter

PAS staining

Van Gieson+