Oral cavity
Inflammatory (noninfectious) lesions
Hyaline ring-like structures

Topic Completed: 1 February 2013

Revised: 31 January 2019

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PubMed Search: Hyaline ring-like structures

Charu Thakral, M.D.
Page views in 2019: 433
Page views in 2020 to date: 62
Cite this page: Thakral C Hyaline ring-like structures. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavityhyalineringlikestructures.html. Accessed February 23rd, 2020.
Definition / general
  • Rarely associated with chronic periostitis, edentulous patients
  • May be a degenerative change in vessel walls from vasculitis or a reaction to legume cells at various stages of digestion
  • Central lesions are asymptomatic, peripheral lesions present as painless submucosal swellings
  • Also called pulse granuloma (pulse is edible seed of legumes), oral vegetable granuloma, giant cell hyaline angiopathy
Case reports
  • Excision or curettage
Clinical images

Images hosted on other servers:

Ulcero-proliferative growth

Microscopic (histologic) description
  • Hyaline ring-like structures, some containing granular necrotic material that surrounds giant cells, vessels, collagen and is itself surrounded by chronic inflammatory cells
Microscopic (histologic) images

Images hosted on other servers:

Granuloma with eosinophilic ulcer

Muscle cells

Foreign body giant cell

Eosinophilic vegetable matter in cyst

PAS+, Alcian blue+

Vegetable matter

PAS staining

Van Gieson+

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