Oral cavity
Minor salivary gland tumors / lesions
Inverted ductal papilloma

Author: Nella Cristina Fernandez, M.D. (see Authors page)

Revised: 27 April 2018, last major update January 2014

Copyright: (c) 2004-2018, PathologyOutlines.com, Inc.

PubMed Search: Inverted ductal papilloma minor salivary glands

Cite this page: Fernandez, N.C. Inverted ductal papilloma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavityinvertedpapilloma.html. Accessed November 18th, 2018.
Definition / general
Clinical features
Case reports
Gross description
Microscopic (histologic) description
  • Appears as dilated duct of minor salivary gland filled with papillae with fibrovascular cores, lined by a thick layer of nonkeratinizing stratified squamous and basaloid epithelium with numerous invaginations and cleft-like narrow spaces
  • Papillae contain cuboidal or columnar duct cells with occasional mucous goblet cells and microcysts
  • No atypia; mitotic figures are rare (Barnes: Pathology and Genetics of Head and Neck Tumours, 1st Edition, 2005)
Microscopic (histologic) images

Images hosted on other servers:


HPV in oral inverted papilloma

HPV in endophytic
component of
oral inverted
ductal papilloma

HPV6 / 11+ by ISH


Differential diagnosis