Oral cavity
Infectious mononucleosis

Author: Patricia DeVilliers, DDS, MS (see Authors page)

Revised: 16 April 2018, last major update August 2012

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PubMed Search: Infectious mononucleosis oral cavity

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Cite this page: DeVilliers, P. Infectious mononucleosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/oralcavitymono.html. Accessed January 22nd, 2019.
Definition / general
  • Acute pharyngitis and tonsillitis with gray-white exudate, lymphadenopathy in neck
  • Due to Epstein-Barr virus infection
Microscopic (histologic) description
  • Tonsil: reactive lymphoid hyperplasia (polymorphous transformed lymphocytes) with extensive immunoblastic proliferation in sheets and nodules, marked atypia resembling Reed-Sternberg cells (Am J Surg Pathol 1987;11:122)
Microscopic (histologic) images

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Peripheral blood lymphocytosis

Reactive lymphocytes

Negative stains