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Oral cavity


Infectious mononucleosis

Reviewer: Patricia DeVilliers, D.D.S., M.S. (see Reviewers page)
Revised: 3 October 2012, last major update August 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.


● Acute pharyngitis and tonsillitis with gray-white exudate, lymphadenopathy in neck
● Due to Epstein-Barr virus infection

Micro description

Tonsil - reactive lymphoid hyperplasia (polymorphous transformed lymphocytes) with extensive immunoblastic proliferation in sheets and nodules, marked atypia resembling Reed-Sternberg cells (Am J Surg Pathol 1987;11:122)

Micro images

Peripheral blood lymphocytosis

Reactive lymphocytes

Negative stains

● CD15, CD30

End of Oral cavity > Infectious > Infectious mononucleosis

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